Anthropology & Evolutionary Biology


§ Equal contributors

Julia Schumacher, Holger Herlyn (2018) Correlates of evolutionary rates in the murine sperm proteome. BMC Evolutionary Biology 18:35 paper

Franz Oswald, Patricia Klöble, André Ruland, David Rosenkranz, Bastian Hinz, Falk Butter, Sanja Ramljak, Ulrich Zechner, Holger Herlyn (2017) The FOXP2-driven network in developmental disorders and neurodegeneration. Frontiers in Cellular Neuroscience 11:212 doi: 10.3389/fncel.2017.00212 paper

Holger Herlyn (2017) Enigmatic Gnathostomulida (Gnathifera, Spiralia): About monociliated pharyngeal receptors and the pharyngeal nervous system. Zoomorphology 136:425–434 doi: 10.1007/s00435-017-0369-4 paper

Holger Herlyn (2017) Organization and evolution of the proboscis musculature in avian parasites of the genus Apororhynchus (Acanthocephala: Apororhynchida). Parasitology Research 116:1801–1810 doi:10.1007/s00436-017-5440-z paper

Dennis Kappei, Marion Scheibe, Maciej Paszkowski-Rogacz, Alina Bluhm, Toni Ingolf Gossmann, Mario Dejung, Holger Herlyn, Frank Buchholz, Matthias Mann, Falk Butter (2017) Phylointeractomics reveals conservation and functional evolution of protein binding. Nature Communications 8:14334 doi: 10.1038/ncomms14334 paper

Holger Herlyn, Horst Taraschewski (2017) Evolutionary anatomy of the muscular apparatus involved in the anchoring of Acanthocephala to the intestinal wall of their vertebrate hosts. Parasitology Research 116:1207–1225. doi: 10.1007/s00436-017-5398-x paper

Julia Schumacher, Hans Zischler, Holger Herlyn (2017) Effects of different kinds of essentiality on sequence evolution of human testis proteins. Scientific Reports 7:43534 doi: 10.1038/srep43534 paper

Sanja Ramljak, Holger Herlyn, Inga Zerr (2016) Cellular prion protein (PrPc) and hypoxia: true to each other in good times and in bad, in sickness and in health. Frontiers in Cellular Neuroscience 10:292 doi: 10.3389/fncel.2016.00292 paper

Holger Herlyn (2016) The phylogenetic system of primates - character evolution in the light of a consolidated tree. Organisms Diversity and Evolution 16:689–713 doi: 10.1007/s13127-016-0279-1 paper

Malte Sielaff, Hanno Schmidt, Torsten Struck, David Rosenkranz, David B. Mark Welch, Thomas Hankeln, Holger Herlyn (2016) Phylogeny of Syndermata (syn. Rotifera): Mitochondrial gene order verifies epizoic Seisonidea as sister to endoparasitic Acanthocephala within monophyletic Hemirotifera. Molecular Phylogenetics and Evolution 96:79–92 doi: 10.1016/j.ympev.2015.11.017 paper

Torsten H. Struck, Alexandra R. Wey-Fabrizius, Anja Golombek, Lars Hering, Anne Weigert, Christoph Bleidorn, Sabrina Klebow, Nataliia Iakovenko, Bernhard Hausdorf, Malte Petersen, Patrick Kück, Holger Herlyn, Thomas Hankeln (2014) Platyzoan paraphyly based on phylogenomic data supports a noncoelomate ancestry of Spiralia. Molecular Biology and Evolution 31:1833–1849. doi: 10.1093/molbev/msu143 paper

Marianne Mathäs, Christian Nußhag, Oliver Burk, Ute Gödtel-Armbrust, Holger Herlyn, Leszek Wojnowski, Björn Windshügel (2014) Structural and functional similarity of amphibian constitutive androstane receptor with mammalian pregnane X receptor. PLoS ONE 9:e96263 doi: 10.1371/journal.pone.0096263 paper

Alexandra R. Wey-Fabrizius§, Holger Herlyn§, Benjamin Rieger, David Rosenkranz, Alexander Witek, David B. Mark Welch, Ingo Ebersberger, Thomas Hankeln (2014) Transcriptome data reveal syndermatan relationships and suggest the evolution of endoparasitism in Acanthocephala via an epizoic stage. PLoS ONE 9:e88618 doi: 10.1371/journal.pone.0088618 paper

Julia Schumacher, David Rosenkranz, Holger Herlyn (2014) Mating systems and protein-protein interactions determine evolutionary rates of primate sperm proteins. Proceedings of the Royal Society B 281:20132607 doi: 10.1098/rspb.2013.2607 paper

Julia Schumacher, Sanja Ramljak, Abdul R. Asif, Michael Schaffrath, Hans Zischler, Holger Herlyn (2013) Evolutionary conservation of mammalian sperm proteins associates with overall, not tyrosine, phosphorylation in human spermatozoa. Journal of Proteome Research 12:5370−5382 doi: 10.1021/pr400228c paper

Alexandra Wey-Fabrizius, Lars Podsiadlowski, Holger Herlyn, Thomas Hankeln (2013) Platyzoan mitochondrial genomes. Review. Molecular Phylogenetics and Evolution 69:365–375 doi: 10.1016/j.ympev.2012.12.015 paper

Mathias Weber, Alexandra Wey-Fabrizius, Lars Podsiadlowski, Alexander Witek, Ralph O. Schill, László Sugár, Holger Herlyn§, Thomas Hankeln§ (2013) Phylogenetic analysis of endoparasitic Acanthocephala based on mitochondrial genomes suggests secondary loss of sensory organs. Molecular Phylogenetics and Evolution 66:182–189 doi: 10.1016/j.ympev.2012.09.017 paper

Eva Gleixner, Holger Herlyn, Stefan Zimmerling, Thorsten Burmester, Thomas Hankeln (2012) Testes-specific hemoglobins in Drosophila evolved by a combination of sub- and neofunctionalization after gene duplication. BMC Evolutionary Biology 12:34 doi: 10.1186/1471-2148-12-34 paper

Andreas Prothmann, Irina Laube, Johanna Dietz, Christian Roos, Katja Mengel, Hans Zischler, Holger Herlyn (2012) Sexual size dimorphism predicts rates of sequence evolution of SPerm Adhesion Molecule 1 (SPAM1, also PH-20) in monkeys, but not in hominoids (apes including humans). Molecular Phylogenetics and Evolution 63:52–63 doi: 10.1016/j.ympev.2011.12.008 paper

Yvonne Döring, Ulrich Zechner, Christian Roos, David Rosenkranz, Hans Zischler, Holger Herlyn (2010) Accelerated evolution of Fetuin-A (FETUA, also AHSG) is driven by positive Darwinian selection, not GC-biased gene conversion. Gene 463:49–55 doi: 10.1016/j.gene.2010.04.018 paper  Figure 3

Holger Herlyn, Ulrich Zechner, Franz Oswald, Arne Pfeufer, Hans Zischler, Thomas Haaf (2009) Positive selection at codon 38 of the human KCNE1 (=minK) gene and sporadic absence of 38Ser-coding mRNAs in Gly38Ser heterozygotes. BMC Evolutionary Biology 6:188 doi: 10.1186/1471-2148-9-188 paper

Alexander Witek, Holger Herlyn, Ingo Ebersberger, David B. Mark Welch, Thomas Hankeln (2009) Support for the monophyletic origin of Gnathifera from phylogenomics. Molecular Phylogenetics and Evolution 53:1037–1041 doi: 10.1016/j.ympev.2009.07.031 paper

Santosh Kumar, Huan Qiu, Numan Oezguen, Holger Herlyn, James R. Halpert, Leszek Wojnowski (2009) Ligand diversity of human and chimpanzee CYP3A4: activation of human CYP3A4 by lithocholic acid results from positive selection. Drug Metabolism and Disposition 37:1328–1333  doi: 10.1124/dmd.108.024372 paper

Holger Herlyn, Hans Zischler (2008) The molecular evolution of sperm zonadhesin. Review. International Journal of Developmental Biology 52:781–790 doi: 10.1387/ijdb.082626hh paper

Alexander Witek§, Holger Herlyn§, Achim Meyer, Louis Boell, Georg Bucher, Thomas Hankeln (2008) EST based phylogenomics of Syndermata questions monophyly of Eurotatoria. BMC Evolutionary Biology 8:345  doi: 10.1124/dmd.108.024372 paper

Huan Qiu, Stefan Taudien, Holger Herlyn, Juergen Schmitz, Yuan Zhou, Guopei Chen, Roberta Roberto, Mariano Rocchi, Matthias Platzer, Leszek Wojnowski (2008) CYP3 phylogenomics: evidence for positive selection of CYP3A4 and CYP3A7. Pharmacogenetics and Genomics 18:53–66 doi: 10.1097/FPC.0b013e3282f313f8 paper

Eva Weis, Danuta Galetzka, Holger Herlyn, Eberhard Schneider, Thomas Haaf (2008) Humans and chimpanzees differ in their cellular response to DNA damage and non-coding sequence elements of DNA repair-associated genes. Cytogenetic and Genome Research 122:92–102 doi: 10.1159/000163086 paper

Bernhard Hausdorf, Martin Helmkampf, Achim Meyer, Alexander Witek, Holger Herlyn, Iris Bruchhaus, Thomas Hankeln, Torsten H. Struck, Bernhard Lieb (2007) Spiralian phylogenomics supports the resurrection of Bryozoa comprising Ectoprocta and Entoprocta. Molecular Biology and Evolution 24:2723–2729 doi: 10.1093/molbev/msm214 paper

Holger Herlyn, Hans Zischler (2007) Sequence evolution of the sperm ligand zonadhesin correlates negatively with body weight dimorphism in primates. Evolution (International Journal of Organic Evolution) 61:289–298 doi: 10.1111/j.1558-5646.2007.00035.x paper

Holger Herlyn, Hans Zischler (2006) Primate Genomes. Review. In: Jean-Nicolas Volff (editor) Genome Dynamics, Karger, Basel, pp. 17–32 paper

Holger Herlyn, Hans Zischler (2006) Tandem repetitive D domains of the sperm ligand zonadhesin evolve faster in the paralogue than in the orthologue comparison. Journal of Molecular Evolution 63:602–611 doi: 10.1007/s00239-005-0146-8 paper

Holger Herlyn, Hans Zischler (2005) Sequence evolution, processing, and posttranslational modification of zonadhesin D domains in primates, as inferred from cDNA data. Gene 362:85–97 doi: 10.1016/j.gene.2005.06.009 paper

Holger Herlyn, Hans Zischler (2005) Identification of a positively evolving putative binding region with increased variability in posttranslational motifs in zonadhesin MAM domain 2. Molecular Phylogenetics and Evolution 37:62–72 doi: 10.1016/j.ympev.2005.04.001 paper

Holger Herlyn, Heidi Röhrig (2003) Ultrastructure and overall organization of ligament sac, uterine bell, uterus and vagina in Paratenuisentis ambiguus (Acanthocephala, Eoacanthocephala) - the character evolution within the Acanthocephala. Acta Zoologica 84:239–247 paper

Holger Herlyn, Oliver Piskurek, Jürgen Schmitz, Ulrich Ehlers, Hans Zischler (2003) The syndermatan phylogeny and the evolution of acanthocephalan endoparasitism as inferred from 18S rDNA sequences. Molecular Phylogenetics and Evolution 26:155–164 paper

Holger Herlyn (2002) The musculature of the praesoma in Macracanthorhynchus hirudinaceus (Acanthocephala, Archiacanthocephala) - re-examination and phylogenetic significance. Zoomorphology 121:173–182 paper

Holger Herlyn (2001) First description of an apical epidermis cone in Paratenuisentis ambiguus (Acanthocephala: Eoacanthocephala) and its phylogenetic implications. Parasitology Research 87:306–310 paper

Holger Herlyn, Nadia Martini, Ulrich Ehlers (2001) Organisation of the praesoma of Paratenuisentis ambiguus (Van Cleave, 1921) (Acanthocephala: Eoacanthocephala), with special reference to the lateral sense organs and musculature. Systematic Parasitology 50:105–116 paper

Holger Herlyn, Ulrich Ehlers (2001) Organisation of the praesoma in Acanthocephalus anguillae (Acanthocephala, Palaeacanthocephala) with special reference to the muscular system. Zoomorphology 121:13–18 paper

Nina Hehn, Ulrich Ehlers, Holger Herlyn (2001) Ultrastructure of the acanthella of Paratenuisentis ambiguus (Acanthocephala). Parasitology Research 87:467–471 paper

Holger Herlyn, Ulrich Ehlers (1997) Ultrastructure and function of the pharynx of Gnathostomula paradoxa (Gnathostomulida). Zoomorphology 117:135–145 paper

Institute of Anthropology, Mainz

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